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  • On September 26, UCLA researcher reported the results of a study, which indicated that Asians who're struggling with alcoholism will benefit especially from naltrexone, among three medications authorized by the U.S. Food and Drug Administration (FDA) for that treatment of alcoholism. Recent research has discovered that a gene variant may predict naltrexone treatment success for alcoholism. About 50% of patients of Asian descent use a particular mutation that produces them likely to benefit from naltrexone, weighed against about 20% of Caucasians and much less than 5% of African Americans, said lead study author Lara Ray, an assistant professor of psychology and director in the UCLA Addictions Laboratory. The findings are available online ( within the journal Neuropsychopharmacology and are published within an upcoming print edition with the journal.

    Using two separate drugs to shed weight can be very effective there are combinations in front of the FDA now awaiting approval. When dealing with fat loss and the people who go through it you ought to err on the side of caution and allow the FDA do its job and demand some research be done so the public recognizes the side effects and risks of the medications before we bring them. Keep in mind that drug companies are in business to generate income and that they would say almost anything to keep people on his or her medications.

    Researchers discovered that participants taking this drug for any year, dropped a few pounds within four weeks and have kept the load off throughout the 56 weeks from the study. Contrave is really a combination of the drugs naltrexone and bupropion, which appears to reflect a brand new trend of weight-loss drugs which can be made up of more than one active ingredient, which might make them far better and safer.

    Combo-pilling may be the newest fad or better yet the newest in the future under scrutiny and thus it is just more publicly known recently, comb-pilling for losing weight has been around since the eighties. The biggest reason that employing a combination of pills is becoming popular will be the fact that at the time of right now there aren't any long term prescription weight loss supplements that have been approved by the FDA besides orlistat. The truly disturbing part is the fact that doctors are prescribing these combinations of medications and some of the combinations happen to be rejected or have yet to be approved by the FDA.

    Seizures can be a side effect with Contrave and shouldn't be taken in people who have seizure disorders. The drug could also raise blood pressure level and pulse rate, and mustn't be used in people who have a history of cardiac event or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

    The FDA also warned that Contrave can raise blood pressure levels and heartbeat and must 't be used in patients with uncontrolled high hypertension, in addition to by you are not heart-related and cerebrovascular (circulatory dysfunction impacting your brain) disease. Patients having a history of cardiac event or stroke in the earlier six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave needs to have their heart-rate and pulse monitored regularly. In addition, because the compound includes bupropion, Contrave comes which has a boxed warning to alert physicians and patients on the increased likelihood of suicidal thoughts and behaviors linked to antidepressant drugs. The warning also notes that serious neuropsychiatric events are already reported in patients taking bupropion for smoking cessation.

    "There were no signs of depression or suicidal thoughts in trial participants," said Fujioka.